Niemann-Pick Disease – causes, side effects and treatments at NaturalPedia.com
Thursday, May 24, 2018 by Michelle Simmons
http://www.naturalpedia.com/niemann-pick-disease-causes-side-effects-and-treatments-at-naturalpedia-com.html
Niemann-Pick disease is a group of inherited metabolic disorders in which harmful quantities of fatty lipids build up in the spleen, liver, lungs, bone marrow, and brain. There are four main types of Niemann-Pick disease based on the mutated gene and the signs and symptoms:
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Type A – caused by mutations in the SMPD1 gene. It is the most severe form, develops in early infancy, and is seen primarily in Jewish families.
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Type B – caused by mutations in the SMPD1 gene. Commonly occurs in children, and affects the liver, spleen, and lungs, but generally does not affect the brain.
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Type C1 – caused by mutations in the NPC1 gene. May occur at any age and affect the brain and the viscera.
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Type C2 – caused by homozygous mutation in the NPC2 gene. Similar to type C1, but more severe, and primarily affects the lungs.
Known side effects of Niemann-Pick disease
The side effects of Niemann-Pick disease vary. Side effects of Type A Niemann-Pick disease may include:
- Abdominal swelling within three to six months
- Cherry red spot at the back of the eye
- Feeding difficulties
- Loss of early motor skills, which gets worse over time
Side effects of Type B Niemann-Pick disease may include:
- Abdominal swelling
- Repeated respiratory infections
Side effects of Type C and C1 Niemann-Pick disease may include:
- Difficulty moving limbs that may lead to an unsteady gait, clumsiness, walking problems
- Enlarged spleen
- Enlarged liver
- Jaundice at birth
- Learning difficulties and cognitive decline
- Seizures
- Slurred, irregular speech
- Sudden loss of muscle tone that may lead to falls
- Tremors
- Trouble moving the eyes up and down
Body systems harmed by Niemann-Pick disease
The body systems harmed by Niemann-Pick disease depend on its type. It may harm the digestive, ocular, nervous, respiratory, and excretory systems.
List of foods or nutrients that prevent Niemann-Pick disease
There is no information on what foods or nutrients prevent Niemann-Pick disease.
Treatments, management plans for Niemann-Pick disease
There is no cure for Niemann-Pick disease. Its treatment focuses on reducing the symptoms and delaying the onset of the disease if it is diagnosed early. Treatments include a healthy, low-cholesterol diet, medications, and therapies.
Where to learn more
- Clean Eating 101: Simple Rules To Live A Healthy And Clean Lifestyle
- Easy and Cheap Ways to Eat Organic Food
- Why aren’t more people eating a plant-based diet? It takes some getting used to
- Healthy Living – Definition and How to Go About It
- Herbs.news
Summary
Niemann-Pick disease is a group of inherited metabolic disorders in which harmful quantities of fatty lipids build up in the spleen, liver, lungs, bone marrow, and brain.
Niemann-Pick disease causes various side effects, depending on its type.
Niemann-Pick disease may harm the digestive, ocular, nervous, respiratory, and excretory systems.
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