Myozyme – uses, health risks, and side effects at NaturalPedia.com

Tuesday, September 11, 2018 by

Myozyme is used to treat a genetic glycogen storage disorder known as Pompe disease, or GAA (acid alpha-glucosidase) deficiency, in adult and young patients at least eight years old.

Myozyme has an enzyme that naturally occurs in healthy individuals. Patients with Pompe disease lack this enzyme and the drug helps replace this missing enzyme.

The use of Myozyme may worsen conditions such as heart disease or a breathing disorder.

Myozyme’s generic name is alglucosidase alfa (injection), and its other brand names include Lumizyme.

Known health risks or side effects of Myozyme

Myozyme may cause common side effects such as:

  • Agitation, dizziness, a headache, or twitching muscles
  • Blue lips, feeling hot or feverish, or pale skin
  • Chest discomfort, a cough, a fast heart rate, or rapid breathing
  • Flushing (redness, a tingly feeling, or warmth) or a skin rash
  • Increased sweating, shaking, or tremors
  • Muscle pain or tiredness
  • Nausea or vomiting

You may require immediate medical attention if you experience severe side effects such as:

  • An allergic reaction – Signs may include difficulty breathing; hives; or the swelling of the face, lips, tongue, or throat.
  • Anxiety, confusion, a fast heart rate, or pounding in the neck or ears
  • Blue lips or fingernails, cold hands or feet, cold or clammy skin, or pale skin
  • Bronchospasm – May include a tight feeling in the chest or throat or trouble breathing/wheezing.
  • Convulsions/seizures
  • Fainting, slow breathing (breathing may stop), a slow heart rate, or a weak pulse
  • Feeling like you’re going to pass out, even if you’re already lying down
  • Feeling restless or nervous, nausea, or a severe headache
  • A fever, itching, rash, or sweating
  • Numbness, redness, a tingly feeling, or warmth under the skin

List of organs that might be affected by Myozyme

Myozyme may cause the following complications:

  • Any skin changes (e.g., discoloring, lesions, sores, or ulcers) or
  • Foamy-looking urine
  • Puffy eyes
  • Swelling in the ankles or feet
  • Weight gain

If you think you’ve taken too much of this drug, consult a healthcare professional. If your symptoms are severe, go to the nearest emergency room immediately.

Food items or nutrients that have similar effects to Myozyme

Instead of taking Myozyme, which may have negative side effects, patients with Pompe disease are encouraged to follow a high-protein diet.

Individuals with this condition lose muscle tissue and data suggests that a high-protein diet, together with appropriate exercise, can help delay muscle loss. The recommended diet includes at least 25 to 30 percent proteins, 30 to 35 percent carbohydrates, and 35 to 40 percent fat.

Make sure to space out carbohydrate consumption in small, frequent portions throughout the day to avoid the build-up of glycogen and prevent low blood sugar.

Protein from sources like egg, dairy products, fish, and meat are full of alanine, an important amino acid. Amino acids are the building blocks of proteins and alanine is crucial for glucose metabolism.

Treatment and management options for the side effects of Myozyme

The following treatments and management options can help prevent the side effects associated with Myozyme, like nausea:

  • The “BRAT” diet – The BRAT diet can help reduce nausea because it includes bland foods that can ease your symptoms. Avoid rich or spicy foods because their strong flavors could unsettle your stomach further. Eat bananas, rice, applesauce, and toast instead.
  • Ginger – Ginger can help reduce nausea. Use fresh ginger when cooking or eat a piece of ginger if you feel nauseous. You can also drink ginger tea.
  • Staying hydrated – If you’re suffering from nausea accompanied by vomiting, stay hydrated and drink water throughout the day. Eat salty foods or drink a non-carbonated, sugary drink to restore the sugars and salts that you’ve lost after vomiting.

Where to learn more

Summary

Myozyme is used to treat a glycogen storage disorder known as Pompe disease, or GAA (acid alpha-glucosidase) deficiency, in adult and young patients at least eight years old.

Myozyme may cause common side effects such as muscle pain or tiredness and nausea or vomiting.

Myozyme may cause complications like foamy-looking urine or puffy eyes.

Instead of taking Myozyme, which may have negative side effects, patients with Pompe disease are encouraged to follow a high-protein diet.

The “BRAT” diet, ginger, and staying hydrated can help prevent the side effects associated with Myozyme, like nausea.

Sources include:

EverydayHealth.com

Drugs.com

PompeDiseaseNews.com

MedicalNewsToday.com



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