Fenpyroximate — toxicity, side effects, diseases and environmental impacts

Saturday, December 02, 2017 by

Fenpyroximate is an acaricide (killer of ticks and mites) and insecticide by inhibiting mitochondrial electron transport at the NADH-coenzyme Q oxidoreductase. It is not under any patent and is the International Organization for Standardization common name for tert-butyl – E-alpha(1,3-dimethyl-5-phenoxypyrazol-4-ylmethyleneamino-oxy)-p-toluate.

The compound was analyzed by the World Health Organization’s International Programme on Chemical Safety in 1995, by the Food and Agriculture Organization and the Joint FAO/WHO Meeting on Pesticide Residues in 2010, 1999 and 1996 for residues and in 2007, 2004, and 1995 for toxicology.

Fenpyroximate has been approved in the European Union since May 1, 2009 as an acaricide following a peer review of the risk assessment that was issued on Oct. 16, 2008.

List of known side effects

Most workers who are involved in the manufacture of fenpyroximate report eye irritations. They also complain of skin sensitization, with some patients saying their effects manifesting as urticaria, a kind of skin rash with raised and itchy bumps, and eczema.

Being exposed to fenpyroximate can cause you to have drastic body weight loss because of a serious loss of appetite, to the point that the person becomes emaciated. Prolonged or repeated exposure to this chemical can cause damage to your organs. You can die if you inhale it. Do not delay from seeking medical attention if you swallow it.

Fenpyroximate can also cause blood conditions. Entry through the bloodstream can cause very detrimental effects to the system.

Fenpyroximate is toxic to honeybees and birds. It is detrimental to algal growth. It is very toxic to aquatic life.

Body systems affected by fenpyroximate

Fenpyroximate is bad for the excretory system. It can induce negative hepatocyte effects.

Fenpyroximate is bad for the female reproductive system. It can induce ovarian atrophy.

Fenpyroximate is bad for the digestive system. People who are exposed to it are prone to heavy bouts of diarrhea.

Fenpyroximate is bad for the cardiovascular system. People who are contaminated by it are susceptible to having bradycardia or very slow heartbeats.

Fenpyroximate is bad for the nervous system. One of the more acute effects of exposure to this chemical is the development of Parkinson’s disease, which shows evidence of mitochondrial respiratory Complex I deficiency in the brain, neuronal death, and oxidative stress.

Fenpyroximate is bad for the respiratory system. It can cause severe pulmonary edema.

Items that can contain fenpyroximate

Fenpyroximate is an acaricide and insecticide. It has yet to be patented.

How to avoid fenpyroximate

Workers who handle the manufacture and assembly of fenpyroximate should wear fully protective clothing (long-sleeved shirt and long pants, chemical-resistant gloves, protective eyewear such as goggles or face shield and shoes plus socks) and a self-contained breathing apparatus.

When cleaning an equipment or a container that has been filled with the chemical, do not forget to wear a chemical-resistant apron.

Also, workers who handle the chemical should wash thoroughly with soap and water before chewing gum, drinking, eating, or using tobacco. Remove clothing that has been to the site of the chemical manufacture immediately after work, and wash it before reusing.

Do not enter treatment areas until 12 hours after fenpyroximate has been dispersed.

Never let contaminated water seep into lakes, rivers, and ponds because fenpyroximate is seriously toxic to aquatic organisms.

Where to learn more

Summary

Most workers who are involved in the manufacture of fenpyroximate reported getting eye irritations.

Fenpyroximate can also cause blood conditions.

Fenpyroximate is bad for the excretory, female reproductive, digestive, cardiovascular, nervous, and respiratory systems.

Sources include:

FAO.org

DataSheets.SCBT.com

InChem.org

PubChem.NCBI.NLM.NIH.gov

 



Comments

comments powered by Disqus