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Aczone – uses, health risks, and side effects at

Tuesday, August 07, 2018 by

Aczone (dapsone) is the trade name for a topical gel that is used to treat acne. The anti-infective medication is manufactured by Allergan.

The oral form of dapsone is used to treat leprosy, an infectious disease that causes skin lesions and nerve damage. Oral dapsone is also administered to patients with certain lung and brain infections linked to HIV/AIDS and skin infections. It helps reduce swelling and it prevents the growth of bacteria.

The Food and Drug Administration (FDA) first approved dapsone in 1955.

Known health risks or side effects of Aczone

Topical Aczone may cause side effects such as oily skin, peeling, redness, or skin dryness.

The topical gel can also cause uncommon side effects such as:

  • Bluish-colored lips, fingernails, or palms
  • Dark-colored urine
  • Difficulty breathing
  • Dizziness/lightheadedness
  • Fever
  • A headache
  • Pale skin
  • Rapid heart rate
  • A sore throat
  • Unusual bleeding/bruising
  • Unusual tiredness/weakness

List of organs that might be affected by Aczone

Topical Aczone may cause the following complications:

  • Anaphylaxis/a severe allergic reaction – Signs include difficulty breathing; hives; rash; swelling of the mouth, face, lips, or tongue; or tightness in the chest.
  • Blistered, red, swollen, or severely peeling skin
  • A burning sensation, numbness, or tingling, in the hands or feet
  • Infection – Signs may include chills, fever, or a sore throat.
  • Mental or mood changes
  • Severe stomach pain or vomiting
  • Sudden back pain
  • Suicidal thoughts
  • Unusual weakness or fatigue
  • Yellow or pale skin

Food items or nutrients that have similar effects to Aczone

The following foods or nutrients have similar effects to Aczone, but only antioxidants, omega-3 fatty acids, and milk are effective when consumed. The rest of the remedies must be applied directly to the skin.

  • Aloe vera – Aloe vera gel can help relieve dry skin. Apply the gel on dry skin and let it soak in to achieve the desired effect.
  • Antioxidants and omega-3 fatty acids – Eating foods rich in antioxidants and omega-3s can help repair damaged and dry skin. Foods rich in antioxidants include beans, blueberries, carrots, lentils, peas, and tomatoes. Meanwhile, fish like salmon has omega-3 fatty acids.
  • Coconut oil – Coconut oil can greatly improve skin hydration. It can also increase the number of lipids or fats on the surface of the skin because coconut oil has saturated fatty acids that have emollient properties.
  • Honey – Honey can help treat different types of skin diseases and it can soothe dry skin. Honey is a natural remedy that possesses anti-inflammatory, healing, and moisturizing properties. Use it as a home remedy by applying it directly to any infected area.
  • Milk – Drinking milk can help relieve dry skin. However, milk isn’t as effective when applied directly to the skin.
  • Sunflower seed oil – When used as a moisturizer on the arms, sunflower seed oil can boost hydration.

Treatment and management options for the side effects of Aczone

The treatments and management options can help prevent the side effects associated with Aczone:

  1. Avoiding allergens and irritants – Dry skin can be caused by allergens or irritants like the fabric conditioner you use or the fabric/material of your clothing. Try to determine what triggers a sudden occurrence of dry skin and avoid it.
  2. Using a humidifier – A humidifier in your home can help reduce the dryness caused by home heating systems. While both electric or gas heat can remove moisture from the air, setting a humidifier to 60 percent can help offset this effect.
  3. Wearing insulated gloves – Hands are often exposed to various environmental irritants like dish soap. Sudden drops in temperature can also affect your hands, so wear insulated gloves while doing household chores or when you’re working outside in extreme temperatures to prevent dry and irritated skin.

Where to learn more


Aczone is the trade name for a topical gel that is used to treat acne.

Topical Aczone may cause oily skin, peeling skin, redness, or skin dryness.

Topical Aczone may lead to complications like anaphylaxis, infection, or mental or mood changes.

Aloe vera, coconut oil, honey, milk, and sunflower seed oil have similar effects to Aczone.

Avoiding allergens and irritants; using a humidifier; or wearing insulated gloves can help prevent the side effects associated with Aczone.

Sources include:


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